UNews - Chris Isaac /unews/person/chris-isaac en Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ of Lethbridge iGEM team earns gold for project that designs oral insulin delivery system /unews/article/university-lethbridge-igem-team-earns-gold-project-designs-oral-insulin-delivery-system <div class="field field-name-body field-type-text-with-summary field-label-hidden"> <div class="field-items"> <div class="field-item even" property="rnews:articlebody schema:articleBody"> <p>The Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ of Lethbridge&rsquo;s Collegiate iGEM team set its sights on solving a problem that affects nearly nine per cent of the world&rsquo;s population, and earned a gold medal for their efforts at the recently concluded International Genetically Engineered Machines World Jamboree in Boston, Mass.</p><p>The collegiate team, accompanied by the U of L&rsquo;s High School iGEM entry that achieved a silver medal standing for its project, presented <a href="https://2019.igem.org/Team:Lethbridge" rel="nofollow">Algulin</a>, which is the development of a novel method for the manufacturing and oral delivery of insulin to diabetics.<div class="image-caption-container right" style="width:500px;"><img src="/unews/sites/default/files/iGEM-2019.jpg" title="U of L iGEM collegiate and high school team members and their advisors in Boston. Back row (L–R) Catrione Lee, David Basil, Mark Lea, Dia Koupantsis, Laura Keffer-Wilkes, Thomas Byrne, Angeliki Pantazi and Chris Isaac. Middle (kneeling L–R) Linda He, Dewuni De Silva, Michelle Wu and Luke Saville. Front – Julien Todd." alt=""><div class="image-caption">U of L iGEM collegiate and high school team members and their advisors in Boston. Back row (L–R) Catrione Lee, David Basil, Mark Lea, Dia Koupantsis, Laura Keffer-Wilkes, Thomas Byrne, Angeliki Pantazi and Chris Isaac. Middle (kneeling L–R) Linda He, Dewuni De Silva, Michelle Wu and Luke Saville. Front – Julien Todd.</div></div></p><p>&ldquo;We wanted to do something different and meaningful, something that will have a positive effect on the people around us,&rdquo; says Dia Koupantsis, a third-year biological sciences student. &ldquo;So, we developed the project Algulin, an oral insulin manufactured in microalgae, in an attempt to democratize the manufacturing of insulin so that it can be widely available for individuals who need it.&rdquo;</p><p>Diabetes is a massive global issue that requires lifelong management for those affected, imposing an enormous economic health burden that amounts to a $673 billion global expenditure annually. Currently, the most common method of relieving diabetes symptoms is through painful, expensive insulin injections. Some patients must self-administer the drug up to six times per day.</p><p>After interviewing diabetic patients, doctors and pharmacists, the iGEM team went about trying to find a way to deliver insulin to patients orally. The challenge, which has thwarted previous attempts, is to find a way to get the insulin through the stomach acid and into the small intestine for absorption without becoming seriously degraded. Their solution &ndash; microalgae.</p><p>Algulin is an oral insulin produced in microalgae. After testing three different microalgae, the group determined Cyanidioschyzon merolae, with its innate acid resistant membrane, could survive the stomach environment. Additionally, with a carbohydrate-based cell wall, C. merolae would degrade in the small intestine and allow for the therapeutic insulin to be absorbed through to its intended target &mdash; the portal vein.</p><p>&ldquo;It was a challenging project because it involved working with an organism we&rsquo;d never used before,&rdquo; says Luke Saville, a fourth-year biochemistry student. &ldquo;This promoted challenges in learning how to grow the organism and how to genetically engineer it to produce our insulin.&rdquo;</p><p>U of L chemistry &amp; biochemistry instructor Dr. Angeliki Pantazi is one of the team&rsquo;s faculty mentors and lauds the team for the work they put in and the further potential of their project.</p><p>&ldquo;The gold medal is exciting but it&rsquo;s a little bit less about what we came back with and more about how we are training the next generation of scientists and leaders through these programs,&rdquo; she says. &ldquo;It&rsquo;s a very student-driven program and I was impressed with why they wanted to pursue this project. They were concerned about people not being able to afford insulin and inspired by the first two Canadian scientists who isolated purified insulin and how they didn&rsquo;t patent it for themselves but instead offered it to humankind for free.&rdquo;</p><p>Now that the iGEM season is over, it&rsquo;s up to the group to find possible investors to continue their work and eventually try and get a product to market. The next stage would be performing animal studies to see how the insulin is being transferred into the bloodstream and how it functions.</p><p>&ldquo;I think it has great commercial potential,&rdquo; says Saville. &ldquo;By moving away from injectables and purification free insulin growth, we can dramatically lower the cost of diabetes management while providing a more comfortable way to administer medicine.&rdquo;</p><p>Other members of the collegiate team included: Catrione Lee, Kalob Barr, Jesse Holbein, Allyson Lawrie-White, Landon McCabe, Joshua Omotosho, Kera Whitten and Dong Ju Kim. Graduate student advisors&nbsp;included Sydnee Calhoun,&nbsp;Aubrey Demchuk, Chris Isaac and Kristi Turton while Dr. Trushar Patel (chemistry &amp; biochemistry) was the secondary investigator.</p><p><strong>High school team earns silver</strong></p><p>All four local high schools contributed to the team that presented <a href="https://2019.igem.org/Team:Lethbridge_HS" rel="nofollow">CADAR</a> (CRISPR assisted detection and removal) at the World Jamboree, a project designed to create a rapid diagnostic tool for identifying bacterial pathogens.</p><p>&ldquo;Our team decided to choose CADAR because we saw the increasing prevalence of antibiotic resistance in pathogenic bacteria,&rdquo; says Mark Lea, a Chinook High School graduate who is now in his first year at the U of L. &ldquo;We found, through initial research, that there is a lot of over-prescription of antibiotics that further increases the amount of bacterial resistance. We thought finding an alternative and more novel approach to traditional antibiotic methods of identifying and then eliminating those pathogens would be an interesting project.&rdquo;</p><p>Dr. Laura Keffer-Wilkes, the manager of Synbridge and high school team advisor, says the project was very ambitious for the high school group and she was pleased with the work they put in to try and develop a product that could be used in health care and patient care settings, in processing plants and even ambulances as a means to validate cleaning practices.</p><p>&ldquo;It&rsquo;s really student-driven, so they go after whatever motivates them, whatever passions they have,&rdquo; she says. &ldquo;As a high school instructor, I don&rsquo;t want to stifle their creativity, and they used some very advanced technology in their work.&rdquo;</p><p>The high school team consisted of: Alice Zhang, Andy Sun, Aroma Pageni, David Basil, Dewuni De Silva, Elisha Wong, Julien Todd, Karen He, Linda He, Katie Vienneau, Mark Lea, Michelle Wu, Mina Akbary, Natasha Woitte, Rachel Avileli, Rebecca Avileli, Shada Aborawi and Thomas Byrne.</p> </div> </div> </div> <div class="field field-name-field-op-related-nref field-type-node-reference field-label-above block-title-body"> <h2><span>Related Content</span></h2> <div class="field-items"> <div class="field-item even"><article about="/unews/article/igem-culture-real-driver-student-success" typeof="rNews:Article schema:NewsArticle" class="node node-openpublish-article node-published node-not-promoted node-not-sticky author-trevorkenney odd clearfix" id="node-openpublish-article-10519"> <div class="content clearfix"> <div class="field field-name-field-op-main-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even" rel="rnews:associatedMedia schema:associatedMedia" resource="/unews/sites/default/files/styles/right-sidebar-thumbnails/public/main/articles/iGEM-HS-2019.jpg"><a href="/unews/article/igem-culture-real-driver-student-success"><img typeof="foaf:Image" src="/unews/sites/default/files/styles/right-sidebar-thumbnails/public/main/articles/iGEM-HS-2019.jpg" width="116" height="80" alt="" /></a></div></div></div><span property="rnews:name schema:name" content="iGEM culture the real driver of student success" class="rdf-meta"></span> <h3 property="rnews:name schema:name" datatype="" class="node-title"><a href="/unews/article/igem-culture-real-driver-student-success" title="iGEM culture the real driver of student success">iGEM culture the real driver of student success</a></h3> </div> </article> </div> </div> </div> <div class="field-group-format group_related_topics field-group-div group-related-topics block-title-body speed-fast effect-none"><h2><span>Related Topics</span></h2><div class="field field-name-opencalais-organization-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Organization:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/organization/igem" typeof="skos:Concept" property="rdfs:label skos:prefLabel">iGEM</a></div><div class="field-item odd"><a href="/unews/organization/department-chemistry-biochemistry" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Department of Chemistry &amp; Biochemistry</a></div><div class="field-item even"><a href="/unews/organization/faculty-arts-science" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Faculty of Arts &amp; Science</a></div></div></div><div class="field field-name-opencalais-person-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Person:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/person/catrione-lee" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Catrione Lee</a></div><div class="field-item odd"><a href="/unews/person/david-basil" typeof="skos:Concept" property="rdfs:label skos:prefLabel">David Basil</a></div><div class="field-item even"><a href="/unews/person/mark-lea" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Mark Lea</a></div><div class="field-item odd"><a href="/unews/person/dia-koupantsis" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Dia Koupantsis</a></div><div class="field-item even"><a href="/unews/person/laura-keffer-wilkes" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Laura Keffer-Wilkes</a></div><div class="field-item odd"><a href="/unews/person/thomas-byrne" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Thomas Byrne</a></div><div class="field-item even"><a href="/unews/person/angeliki-pantazi" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Angeliki Pantazi</a></div><div class="field-item odd"><a href="/unews/person/chris-isaac" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Chris Isaac</a></div><div class="field-item even"><a href="/unews/person/linda-he" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Linda He</a></div><div class="field-item odd"><a href="/unews/person/dewuni-de-silva" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Dewuni De Silva</a></div><div class="field-item even"><a href="/unews/person/michelle-wu" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Michelle Wu</a></div><div class="field-item odd"><a href="/unews/person/luke-saville" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Luke Saville</a></div><div class="field-item even"><a href="/unews/person/julien-todd" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Julien Todd</a></div></div></div></div><span property="rnews:name schema:name" content="Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ of Lethbridge iGEM team earns gold for project that designs oral insulin delivery system" class="rdf-meta"></span> Thu, 21 Nov 2019 18:34:18 +0000 trevor.kenney 10520 at /unews U of L iGEM teams tackling relevant issues, awarded gold and silver at Giant Jamboree /unews/article/u-l-igem-teams-tackling-relevant-issues-awarded-gold-and-silver-giant-jamboree <div class="field field-name-body field-type-text-with-summary field-label-hidden"> <div class="field-items"> <div class="field-item even" property="rnews:articlebody schema:articleBody"> <p>The Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ of Lethbridge&rsquo;s iGEM students have proven once again they are among the best and brightest scientists in the synthetic biology field.<div class="image-caption-container right" style="width:450px;"><img src="/unews/sites/default/files/iGEM1.jpg" title="The U of L&amp;#039;s collegiate iGEM representatives who presented in Boston." alt=""><div class="image-caption">The U of L&#039;s collegiate iGEM representatives who presented in Boston.</div></div></p><p>From over 300 teams, representing countries from all over the world, the U of L&rsquo;s collegiate team secured a gold medal and the high school entry a silver at the 2018 International Genetically Engineered Machine (iGEM) competition in Boston, MA.</p><p>The collegiate team&rsquo;s project <em>VINCEnT</em> focused on developing tools for other synthetic biology researchers. Targeting specific tissues, cell types, or cellular organelles is important for the correct treatment of many diseases. The U of L team created software that would help others overcome these problems. The team members also demonstrated how they can successfully encapsulate cargo within P22 &ldquo;nanocompartments&rdquo; that can target Zebra and Quagga mussels with species-specific toxins. One of the largest problems facing Alberta waterways, Zebra and Quagga mussels are considered aquatic invasive species and a threat to the Alberta economy, specifically agriculture, tourism and recreation as they destroy natural lake ecosystems and fisheries. Work on this application will continue in the future.<div class="image-caption-container right" style="width:400px;"><img src="/unews/sites/default/files/iGEM2.jpg" title="The U of L&amp;#039;s high school team impressed with a silver medal standing." alt=""><div class="image-caption">The U of L&#039;s high school team impressed with a silver medal standing.</div></div></p><p>The U of L team of Sydnee Calhoun, Kristi Turton, Catrione Lee and Luke Saville presented at the jamboree and were supported by team members Keith Aiken, Maya Degrood, Simmone D&rsquo;Souza, Travis Haight, DJ Kim, Jessica Semmelrock, Reanna Takeyasu and David Tobin. Aubrey Demchuk, Graeme Glaister, Zak Stinson and secondary investigator Dr. Trushar Patel served as advisors.</p><p>The Lethbridge high school team is comprised of students from Winston Churchill High School, Lethbridge Collegiate Institute, Chinook High School and Catholic Central High School. Members Mark Lea, Michelle Wu and Andy Sun travelled to Boston to represent the team. Their project, <em>Cu Later</em>, described a method for the capture and removal of metals from tailings ponds and effluent water using an engineered bacteriophage system and received a silver medal and nomination for best model.</p><p>Dewuni De Silva, Aidan Sander, Nicolas Parra, Aroma Pageni, Rebecca Avileli, Tyler Black, Logan Black, Alice Zhang, Karen He, Mina Akbary-Zheng, Emily Huynh and Nimaya De Silva supported their teammates&rsquo; efforts from Lethbridge. Recruitment for the 2019 Lethbridge high school iGEM team will begin in January.</p><p>Representatives from the Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ of Lethbridge were also involved in core activities for the iGEM Giant Jamboree. Dr. Hans-Joachim Wieden, also a primary investigator for the U of L collegiate team, was one of the competition judges, and Chris Isaac, U of L biochemistry graduate student, participated in the iGEM Safety Committee.</p><p>The projects and accomplishments of the <a href="http://2018.igem.org/Team:Lethbridge" rel="nofollow">university</a> and <a href="http://2018.igem.org/Team:Lethbridge_HS" rel="nofollow">high school</a> teams are available on their wiki websites. Also, follow the high school team&rsquo;s progress on social media: <a href="https://twitter.com/LethHS_iGEM" rel="nofollow">@LethHS_iGEM</a> and <a href="https://www.facebook.com/lethbridgehsiGEM/" rel="nofollow">@lethbridgehsiGEM</a>. The U of L team can be followed here: <a href="https://twitter.com/LethbridgeiGEM" rel="nofollow">@LethbridgeiGEM</a>.</p> </div> </div> </div> <div class="field-group-format group_related_topics field-group-div group-related-topics block-title-body speed-fast effect-none"><h2><span>Related Topics</span></h2><div class="field field-name-opencalais-organization-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Organization:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/organization/igem" typeof="skos:Concept" property="rdfs:label skos:prefLabel">iGEM</a></div></div></div><div class="field field-name-opencalais-person-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Person:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/person/sydnee-calhoun" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Sydnee Calhoun</a></div><div class="field-item odd"><a href="/unews/person/kristi-turton" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Kristi Turton</a></div><div class="field-item even"><a href="/unews/person/catrione-lee" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Catrione Lee</a></div><div class="field-item odd"><a href="/unews/person/chris-isaac" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Chris Isaac</a></div><div class="field-item even"><a href="/unews/person/luke-saville" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Luke Saville</a></div><div class="field-item odd"><a href="/unews/person/keith-aiken" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Keith Aiken</a></div><div class="field-item even"><a href="/unews/person/maya-degrood" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Maya Degrood</a></div><div class="field-item odd"><a href="/unews/person/simmone-d%E2%80%99souza" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Simmone D’Souza</a></div><div class="field-item even"><a href="/unews/person/travis-haight" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Travis Haight</a></div><div class="field-item odd"><a href="/unews/person/dj-kim" typeof="skos:Concept" property="rdfs:label skos:prefLabel">DJ Kim</a></div><div class="field-item even"><a href="/unews/person/jessica-semmelrock" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Jessica Semmelrock</a></div><div class="field-item odd"><a href="/unews/person/reanna-takeyasu-and-david-tobin-aubrey-demchuk" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Reanna Takeyasu and David Tobin. Aubrey Demchuk</a></div><div class="field-item even"><a href="/unews/person/graeme-glaister" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Graeme Glaister</a></div><div class="field-item odd"><a href="/unews/person/zak-stinson" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Zak Stinson</a></div><div class="field-item even"><a href="/unews/person/trushar-patel" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Trushar Patel</a></div><div class="field-item odd"><a href="/unews/person/hans-joachim-wieden" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Hans-Joachim Wieden</a></div></div></div></div><span property="rnews:name schema:name" content="U of L iGEM teams tackling relevant issues, awarded gold and silver at Giant Jamboree" class="rdf-meta"></span> Tue, 06 Nov 2018 21:13:23 +0000 trevor.kenney 9970 at /unews U of L student joins iGEM delegation to present at Biological Weapons Convention /unews/article/u-l-student-joins-igem-delegation-present-biological-weapons-convention <div class="field field-name-body field-type-text-with-summary field-label-hidden"> <div class="field-items"> <div class="field-item even" property="rnews:articlebody schema:articleBody"> <p>The Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ of Lethbridge&rsquo;s iGEM (International Genetically Engineered Machine) team made quite a splash at November&rsquo;s annual jamboree, providing the springboard for one U of L student to participate on the world stage.</p><p>The iGEM team&rsquo;s project focused on ways to make synthetic biology safe and available for everyone, says Chris Isaac (BSc&rsquo; 17), a biochemistry master&rsquo;s student who has participated in iGEM since he was a Grade 11 student at Chinook High School.<div class="image-caption-container right" style="width:350px;"><img src="/unews/sites/default/files/ChrisIsaacMain.jpg" alt=""></div></p><p>&ldquo;We presented these results in Boston and we drew the attention of iGEM itself, the FBI and the Dutch Institute for Public Health,&rdquo; he says. &ldquo;Our team was trying to develop a cell-free synthetic biology system to bring this technology to as many people as possible and make sure that it&rsquo;s democratically spread out. Then we realized that this tool, as useful as it is, also opens up unforeseen biosecurity risks.&rdquo;</p><p>The iGEM ambassador to Latin America approached Isaac and suggested he apply to the iGEM delegate program. He did and was chosen to be part of the iGEM Foundation&rsquo;s delegation to the Meeting of States Parties to the Biological Weapons Convention (BWC) in Geneva from Dec. 4 to 8. Isaac was one of five students in the delegation. They attended the plenary sessions and presented to delegates from around the world at a side event.</p><p>&ldquo;We spoke to delegates over lunch and talked about our experiences in iGEM and how they relate to biosecurity and provided our thoughts about how to make biosecurity practices better,&rdquo; says Isaac. &ldquo;The reception was very warm. Those who attended the meeting were excited to hear our perspectives, they asked thoughtful questions and the discussion was very productive.&rdquo;</p><p>As it stands now, the risks that would come with making genetically recoded cell-free systems exist only in theory, but Isaac says the tools are on the horizon given advancing technology. While cell-free synthetic biology has the possibility of doing great good, there is also the potential for great harm if proper controls are not in place.</p><p>&ldquo;The issue that we&rsquo;ve identified with this technology is that it might allow individuals to bypass current screening procedures in terms of DNA synthesis, which is a service that researchers around the world rely on extensively,&rdquo; he says.</p><p>When researchers request a certain DNA sequence from a bioscience company, the company&rsquo;s software analyzes the request and will deny it if the requested sequence is too close of a match to a toxin, such as anthrax or botulinum toxin (botox). Using a novel genetic code to interpret a sequence would allow a request to bypass the current screening protocols in place at synthesis companies.</p><p>&ldquo;We, as Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ and synthetic biologists on the frontline of technological development, need to be better connected with the people who are talking about policy and regulations. We need more science policy advocates with the ability to influence policy from the top down and also guide cultural changes from the bottom up,&rdquo; says Isaac.</p> </div> </div> </div> <div class="field-group-format group_related_topics field-group-div group-related-topics block-title-body speed-fast effect-none"><h2><span>Related Topics</span></h2><div class="field field-name-opencalais-organization-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Organization:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/organization/faculty-arts-and-science" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Faculty of Arts and Science</a></div><div class="field-item odd"><a href="/unews/organization/department-chemistry-biochemistry" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Department of Chemistry &amp; Biochemistry</a></div></div></div><div class="field field-name-opencalais-person-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Person:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/person/chris-isaac" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Chris Isaac</a></div></div></div></div><span property="rnews:name schema:name" content="U of L student joins iGEM delegation to present at Biological Weapons Convention" class="rdf-meta"></span> Fri, 22 Dec 2017 17:21:13 +0000 caroline.zentner 9400 at /unews Excelling on the world stage /unews/article/excelling-world-stage-0 <div class="field field-name-field-op-author field-type-node-reference field-label-hidden"><div class="field-items"><div class="field-item even" rel="rnews:creator schema:creator"><div class="view view-openpublish-related-content view-id-openpublish_related_content view-display-id-block_1 view-dom-id-64ed91e9f1642da5113a25513ebdf64b"> <div class="view-content"> <div class="views-row views-row-1 views-row-odd views-row-first views-row-last"> <div class="views-field views-field-title"> <span class="views-label views-label-title">by</span> <span class="field-content"><a href="/unews/profile/dana-yates">Dana Yates</a></span> </div> <div class="views-field views-field-created"> <span class="field-content">November 22, 2013</span> </div> </div> </div> </div></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"> <div class="field-items"> <div class="field-item even" property="rnews:articlebody schema:articleBody"> <p><span>Learning from the best &ndash; that&rsquo;s exactly what a group of research-focused students is doing at the Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ of Lethbridge.&nbsp;</span></p><p><span>Members of the U of L&rsquo;s International Genetically Engineered Machine (iGEM) team are part of a phenomenon that began 10 years ago as a course at the Massachusetts Institute of Technology (MIT). Today, the annual iGEM contest is the world&rsquo;s leading undergraduate synthetic biology competition &ndash; and each year, U of L students regularly rank among the top iGEM teams worldwide.&nbsp;</span></p><p><span>An emerging field, synthetic biology sees cells, enzymes and metabolic pathways as more than biological entities; they&rsquo;re sophisticated parts that can be programmed like machines to perform specific activities. As a result, research in synthetic biology is opening up remarkable possibilities in such sectors as agriculture, pharmaceutical, medical diagnostics, clean energy and resource extraction.&nbsp;</span>In 2011, for example, U of L students developed a petrochemical-eating bacteria that could be used to help clean up water in tailings ponds, a discovery that placed the Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬&rsquo;s iGEM team among the top 16 competitors in the world, alongside students from Harvard Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬, MIT, the Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ of Washington and Johns Hopkins Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬.</p><p><span>This October, the U of L&rsquo;s iGEM team once again demonstrated its strong innovation abilities. In addition to creating a bioengineering part that works like a zip drive, compressing genetic information, the team developed software that rapidly determines what DNA sequences are compatible to compress together. These inventions, which will allow future bioengineers more flexibility in their research, captured top prize in the 2013 North American iGEM Regional Jamboree held in Toronto. Moreover, the first-place finish secured the team &ndash; made up of Dustin Smith (BSc &rsquo;13), Graeme Glaister, Jenna Friedt (BSc &rsquo;11, MSc &rsquo;13), Suneet Kharey, Harland Brandon (BSc &rsquo;13) and Zak Stinson &ndash; a spot in the international iGEM competition at MIT in November, where the team claimed two&nbsp;prominent awards.</span></p><p><div class="image-caption-container right" style="width:499px;"><img src="/unews/sites/default/files/1_1.jpg" title="iGEM students are representing the U of L on the world stage. Back row (L-R) Harland Brandon (BSc ’13), Dustin Smith (BSc ’13), Graeme Glaister, Zak Stinson and Dr. H.J. Wieden (faculty advisor). Front row (L-R) Suneet Kharey and Jenna Friedt (BSc ’11, MSc ’13). (Photo by Leslie Ohene-Adjei)" alt=""><div class="image-caption">iGEM students are representing the U of L on the world stage. Back row (L-R) Harland Brandon (BSc ’13), Dustin Smith (BSc ’13), Graeme Glaister, Zak Stinson and Dr. H.J. Wieden (faculty advisor). Front row (L-R) Suneet Kharey and Jenna Friedt (BSc ’11, MSc ’13). (Photo by Leslie Ohene-Adjei)</div></div></p><p><span>Providing students with the opportunity to compete against teams from around the world is just one way iGEM benefits its participants, says U of L biochemistry professor Dr. Hans-Joachim (H.J.) Wieden. Considered the driving force behind the U of L&rsquo;s iGEM teams, Wieden serves as the students&rsquo; advisor and coach. He is also a highly respected researcher in his own right.&nbsp;</span></p><p><span>Director of the <a href="http://www.uleth.ca/artsci/news/2012/03/alberta-rna-research-and-training-institute" rel="nofollow">Alberta RNA (</a>ribonucleic acid) <a href="http://www.uleth.ca/artsci/news/2012/03/alberta-rna-research-and-training-institute" rel="nofollow">Research and Training Institute at the U of L</a>, Wieden was also recently appointed the Innovates Centre of Research Excellence (iCORE) Chair of Bioengineering. Funded by a $2-million investment from Alberta Innovates-Technology Futures, the role enables Wieden&rsquo;s research team to study how biological systems can be engineered to achieve breakthroughs in materials science, chemistry, biochemistry, health and nanoscience.&nbsp;</span></p><p><span>&ldquo;iGEM enables students to get their first taste of research,&rdquo; says Wieden. &ldquo;They understand the goal of the project, and learn how to think outside of the box, troubleshoot and apply their knowledge to create scientific discoveries. All of this unlocks students&rsquo; creativity.&rdquo;&nbsp;</span></p><p><span>What&rsquo;s more, he continues, iGEM cultivates students&rsquo; entrepreneurial potential. The teams manage their own projects and raise funds to support their work, as well as learn how to communicate effectively and connect their work to real-world needs. Finally, as young researchers themselves, they come to realize the importance of supporting the forward-thinking scientists of the future: high school students.&nbsp;</span></p><p><span>To that end, U of L students have started iGEM teams in high schools in southern Alberta. And those high school students are following in the success of their older counterparts. Earlier this year, in fact, a team of Lethbridge high school students representing schools from across the city, won the Green Brick grand prize at iGEM&rsquo;s international High School Jamboree at MIT, as well as trophies for Best New Biobrick Natural for their engineered DNA part and Best Wiki, the website used to display their project. &nbsp;</span></p><p><span>Advised by Wieden as well as U of L undergraduate and graduate students, the high school team &ndash; consisting of 22 students from Lethbridge-area high schools, including Kieran McCormack, Chris Isaac, Elaine Bird, Fiona Spitzig, Yoyo Yao, Patrick O&rsquo;Donnell and Katie Thomas, who represented the team at the jamboree &ndash; successfully created a longer lasting form of Oxytocin. A hormone that&rsquo;s most-commonly used to aid childbirth, Oxytocin degrades quickly and soon becomes unstable, making it expensive and difficult to store.&nbsp;</span></p><p><span>While such complex projects can be challenging for high school students, the research experience is invaluable, says former iGEM high school team member Erin Kelly.&nbsp;</span></p><p><span>&ldquo;Being on the high school team was a steep learning curve, but I learned research methods through hands-on experience and that definitely made the transition to university easier,&rdquo; says Kelly. Now a second-year biochemistry student at the U of L, she serves as an advisor to the current iGEM high school team along with fourth-year neuroscience student Isaac Ward and master of biochemistry student Mackenzie Coatham (BSc &rsquo;12).</span></p><p><div class="image-caption-container right" style="width:499px;"><img src="/unews/sites/default/files/2.jpg" title="U of L iGEM students Isaac Ward, Mackenzie Coatham (BSc ’12), Harland Brandon (BSc ’13) and Erin Kelly are using their research and entrepreneurial skills to launch their own company. (Photo by Leslie Ohene-Adjei)" alt=""><div class="image-caption">U of L iGEM students Isaac Ward, Mackenzie Coatham (BSc ’12), Harland Brandon (BSc ’13) and Erin Kelly are using their research and entrepreneurial skills to launch their own company. (Photo by Leslie Ohene-Adjei)</div></div></p><p><span>The trio, all former members of the undergraduate iGEM team, have used their resulting research and entrepreneurial skills to launch the spinoff company Synbiologica Ltd. Along with Brandon (now a U of L master&rsquo;s student in biochemistry), and U of L neuroscience professor Dr. Gerlinde Metz and Wieden as advisors, the group is in the process of patenting their big idea &ndash; a biomedical technology that provides rapid hormone-detection results. Their idea is expected to be 93 per cent more cost-effective than traditional antibody technology, bringing the next generation of hormone detection to the research, agriculture and medical markets.&nbsp;</span></p><p><span>In recognition of its scientific innovation, the Synbiologica team has earned numerous accolades. They include <a href="http://www.uleth.ca/artsci/news/2013/06/synbiologica-team-wins-2013-chinook-entrepreneur-challenge" rel="nofollow">winning</a> $10,000 in the South Venture Business Plan Competition and taking first place in the Tech Stream side of the Chinook Entrepreneurial Challenge, an annual business-planning competition hosted by Community Futures Lethbridge Region. The group received an additional $10,000 in cash, a one-year lease on space in the tecconnect: An Alberta centre for new commerce &ndash; a high-tech business incubator operated by Economic Development Lethbridge &ndash; plus a range of other in-kind prizes, including business consulting from MNP and ActionCOACH, and several thousand dollars worth of media services.&nbsp;</span></p><p><span>&ldquo;iGEM gave us the motivation and skills to explore multidisciplinary research,&rdquo; says Ward, chief executive officer of Synbiologica. &ldquo;And from there, we realized that we don&rsquo;t have to follow the usual career route. We can create our own jobs.&rdquo;&nbsp;</span></p> </div> </div> </div> <div class="field-group-format group_related_topics field-group-div group-related-topics block-title-body speed-fast effect-none"><h2><span>Related Topics</span></h2><div class="field field-name-opencalais-city-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">City:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/city/toronto" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Toronto</a></div></div></div><div class="field field-name-opencalais-company-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Company:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/company/synbiologica-ltd" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Synbiologica Ltd.</a></div></div></div><div class="field field-name-opencalais-person-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Person:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/person/mackenzie-coatham" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Mackenzie Coatham</a></div><div class="field-item odd"><a href="/unews/person/elaine-bird" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Elaine Bird</a></div><div class="field-item even"><a href="/unews/person/erin-kelly" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Erin Kelly</a></div><div class="field-item odd"><a href="/unews/person/dustin-smith" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Dustin Smith</a></div><div class="field-item even"><a href="/unews/person/donnell-thomas" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Donnell Thomas</a></div><div class="field-item odd"><a href="/unews/person/jenna-friedt" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Jenna Friedt</a></div><div class="field-item even"><a href="/unews/person/isaac-ward" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Isaac Ward</a></div><div class="field-item odd"><a href="/unews/person/katie-thomas" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Katie Thomas</a></div><div class="field-item even"><a href="/unews/person/gerlinde-metz" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Gerlinde Metz</a></div><div class="field-item odd"><a href="/unews/person/hans-joachim-wieden" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Hans-Joachim Wieden</a></div><div class="field-item even"><a href="/unews/person/fiona-spitzig" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Fiona Spitzig</a></div><div class="field-item odd"><a href="/unews/person/chris-isaac" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Chris Isaac</a></div><div class="field-item even"><a href="/unews/person/kieran-mccormack" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Kieran McCormack</a></div></div></div><div class="field field-name-opencalais-technology-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Technology:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/technology/igem" typeof="skos:Concept" property="rdfs:label skos:prefLabel">iGEM</a></div></div></div></div><span property="rnews:name schema:name" content="Excelling on the world stage" class="rdf-meta"></span> Fri, 22 Nov 2013 15:14:55 +0000 david.kirby 5810 at /unews Excelling on the world stage /unews/article/excelling-world-stage <div class="field field-name-body field-type-text-with-summary field-label-hidden"> <div class="field-items"> <div class="field-item even" property="rnews:articlebody schema:articleBody"> <p>Learning from the best &ndash; that&rsquo;s exactly what a group of research-focused students is doing at the Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ of Lethbridge.</p><p>Members of the U of L&rsquo;s International Genetically Engineered Machine (iGEM) team are part of a phenomenon that began 10 years ago as a course at the Massachusetts Institute of Technology (MIT). Today, the annual iGEM contest is the world&rsquo;s leading undergraduate synthetic biology competition &ndash; and each year, U of L students regularly rank among the top iGEM teams worldwide.<div class="image-caption-container right" style="width:500px;"><img src="/unews/sites/default/files/IGEMKids-main.jpg" title="Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ of Lethbridge iGEM students Isaac Ward, Mackenzie Coatham, Harland Brandon and Erin Kelly are among the best young researchers in the world." alt=""><div class="image-caption">Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ of Lethbridge iGEM students Isaac Ward, Mackenzie Coatham, Harland Brandon and Erin Kelly are among the best young researchers in the world.</div></div></p><p>An emerging field, synthetic biology sees cells, enzymes and metabolic pathways as more than biological entities; they&rsquo;re sophisticated parts that can be programmed like machines to perform specific activities. As a result, research in synthetic biology is opening up remarkable possibilities in such sectors as agriculture, pharmaceutical, medical diagnostics, clean energy and resource extraction. In 2011, for example, U of L students developed a petrochemical-eating bacteria that could be used to help clean up water in tailings ponds, a discovery that placed the Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬&rsquo;s iGEM team among the top 16 competitors in the world, alongside students from Harvard Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬, MIT, the Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ of Washington and Johns Hopkins Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬.</p><p>This October, the U of L&rsquo;s iGEM team once again demonstrated its strong innovation abilities. In addition to creating a bioengineering part that works like a zip drive, compressing genetic information, the team developed software that rapidly determines what DNA sequences are compatible to compress together. These inventions, which will allow future bioengineers more flexibility in their research, captured top prize in the 2013 North American iGEM Regional Jamboree held in Toronto. Moreover, the first-place finish secured the team &ndash; made up of Dustin Smith (BSc &rsquo;13), Graeme Glaister, Jenna Friedt (BSc &rsquo;11, MSc&rsquo;13), Suneet Kharey, Harland Brandon (BSc &rsquo;12) and Zak Stinson &ndash; a spot in the international iGEM competition, which will be held at MIT in November.</a></p><p>Providing students with the opportunity to compete against teams from around the world is just one way iGEM benefits its participants, says U of L biochemistry professor Dr. Hans-Joachim (H.J.) Wieden. Considered the driving force behind the U of L&rsquo;s iGEM teams, Wieden serves as the students&rsquo; advisor and coach. He is also a highly respected researcher in his own right.</p><p>Director of the Alberta RNA (Ribonucleic acid) Research and Training Institute at the U of L, Wieden was also recently appointed the Innovates Centre of Research Excellence (iCORE) Chair of Bioengineering. Funded by a $2-million investment from Alberta Innovates-Technology Futures, the role enables Wieden&rsquo;s research team to study how biological systems can be engineered to achieve breakthroughs in materials science, chemistry, biochemistry, health and nanoscience.</p><p>&ldquo;iGEM enables students to get their first taste of research,&rdquo; says Wieden. &ldquo;They understand the goal of the project, and learn how to think outside of the box, troubleshoot and apply their knowledge to create scientific discoveries. All of this unlocks students&rsquo; creativity.&rdquo;</p><p>What&rsquo;s more, he continues, iGEM cultivates students&rsquo; entrepreneurial potential. The teams manage their own projects and raise funds to support their work, as well as learn how to communicate effectively and connect their work to real-world needs. Finally, as young researchers themselves, they come to realize the importance of supporting the forward-thinking scientists of the future: high school students.</p><p>To that end, U of L students have started iGEM teams in high schools in southern Alberta. And those high school students are following in the success of their older counterparts. Earlier this year, in fact, a team of Lethbridge high school students representing schools from across the city, won the Green Brick grand prize at iGEM&rsquo;s international High School Jamboree at MIT, as well as trophies for Best New Biobrick Natural for their engineered DNA part and Best Wiki, the website used to display their project. </p><p>Advised by Wieden as well as U of L undergraduate and graduate students, the high school team &ndash; consisting of 22 students from Lethbridge-area high schools, including Keiran McCormack, Chris Isaac, Elaine Bird, Fiona Spitzig, Yoyo Yao, Patrick O&#39;Donnell and Katie Thomas, who represented the team at the jamboree &ndash; successfully created a longer lasting form of Oxytocin. A hormone that&rsquo;s most-commonly used to aid childbirth, Oxytocin degrades quickly and soon becomes unstable, making it expensive and difficult to store.</p><p>While such complex projects can be challenging for high school students, the research experience is invaluable, says former iGEM high school team member Erin Kelly.</p><p>&ldquo;Being on the high school team was a steep learning curve, but I learned research methods through hands-on experience and that definitely made the transition to university easier,&rdquo; says Kelly. Now a second-year biochemistry student at the U of L, she serves as an advisor to the current iGEM high school team along with fourth-year neuroscience student Isaac Ward and master of biochemistry student Mackenzie Coatham (BSc &rsquo;12).</p><p>The trio, all former members of the undergraduate iGEM team, have used their resulting research and entrepreneurial skills to launch the spinoff company Synbiologica Ltd. Along with Brandon (now a<br />U of L master&rsquo;s student in biochemistry), and U of L neuroscience professor Dr. Gerlinde Metz and Wieden as advisors, the group is in the process of patenting their big idea &ndash; a biomedical technology that provides rapid hormone-detection results. Their idea is expected to be 93 per cent more cost-effective than traditional antibody technology, bringing the next generation of hormone detection to the research, agriculture and medical markets.</p><p>In recognition of its scientific innovation, the Synbiologica team has earned numerous accolades. They include winning $10,000 in the South Venture Business Plan Competition and taking first place in the Tech Stream side of the Chinook Entrepreneurial Challenge, an annual business-planning competition hosted by Community Futures Lethbridge Region. The group received an additional $10,000 in cash, a one-year lease on space in the tecconnect: An Alberta centre for new commerce &ndash; a high-tech business incubator operated by Economic Development Lethbridge &ndash; plus a range of other in-kind prizes, including business consulting from MNP and ActionCOACH, and several thousand dollars worth of media services.</p><p>&ldquo;iGEM gave us the motivation and skills to explore multidisciplinary research,&rdquo; says Ward, chief executive officer of Synbiologica. &ldquo;And from there, we realized that we don&rsquo;t have to follow the usual career route. We can create our own jobs.&rdquo;</p> </div> </div> </div> <div class="field-group-format group_related_topics field-group-div group-related-topics block-title-body speed-fast effect-none"><h2><span>Related Topics</span></h2><div class="field field-name-opencalais-company-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Company:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/company/economic-development-lethbridge" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Economic Development Lethbridge</a></div><div class="field-item odd"><a href="/unews/company/synbiologica-ltd" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Synbiologica Ltd.</a></div></div></div><div class="field field-name-opencalais-industryterm-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">IndustryTerm:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/industry-term/biological-systems" typeof="skos:Concept" property="rdfs:label skos:prefLabel">biological systems</a></div><div class="field-item odd"><a href="/unews/industry-term/antibody-technology" typeof="skos:Concept" property="rdfs:label skos:prefLabel">antibody technology</a></div><div class="field-item even"><a href="/unews/industry-term/clean-energy" typeof="skos:Concept" property="rdfs:label skos:prefLabel">clean energy</a></div><div class="field-item odd"><a href="/unews/industry-term/biomedical-technology" typeof="skos:Concept" property="rdfs:label skos:prefLabel">biomedical technology</a></div></div></div><div class="field field-name-opencalais-naturalfeature-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">NaturalFeature:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/natural-feature/tech-stream" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Tech Stream</a></div></div></div><div class="field field-name-opencalais-organization-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Organization:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/organization/innovates-centre-research-excellence" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Innovates Centre of Research Excellence</a></div><div class="field-item odd"><a href="/unews/organization/research-and-training-institute" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Research and Training Institute</a></div><div class="field-item even"><a href="/unews/organization/johns-hopkins-university" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Johns Hopkins Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬</a></div><div class="field-item odd"><a href="/unews/organization/massachusetts-institute-technology" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Massachusetts Institute of Technology</a></div><div class="field-item even"><a href="/unews/organization/university-lethbridge" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ of Lethbridge</a></div></div></div><div class="field field-name-opencalais-person-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Person:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/person/mackenzie-coatham" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Mackenzie Coatham</a></div><div class="field-item odd"><a href="/unews/person/elaine-bird" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Elaine Bird</a></div><div class="field-item even"><a href="/unews/person/erin-kelly" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Erin Kelly</a></div><div class="field-item odd"><a href="/unews/person/dustin-smith" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Dustin Smith</a></div><div class="field-item even"><a href="/unews/person/donnell-thomas" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Donnell Thomas</a></div><div class="field-item odd"><a href="/unews/person/jenna-friedt" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Jenna Friedt</a></div><div class="field-item even"><a href="/unews/person/isaac-ward" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Isaac Ward</a></div><div class="field-item odd"><a href="/unews/person/katie-thomas" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Katie Thomas</a></div><div class="field-item even"><a href="/unews/person/gerlinde-metz" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Gerlinde Metz</a></div><div class="field-item odd"><a href="/unews/person/hans-joachim" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Hans-Joachim</a></div><div class="field-item even"><a href="/unews/person/fiona-spitzig" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Fiona Spitzig</a></div><div class="field-item odd"><a href="/unews/person/wieden" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Wieden</a></div><div class="field-item even"><a href="/unews/person/chris-isaac" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Chris Isaac</a></div></div></div><div class="field field-name-opencalais-technology-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Technology:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/technology/neuroscience" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Neuroscience</a></div><div class="field-item odd"><a href="/unews/technology/antibody-technology" typeof="skos:Concept" property="rdfs:label skos:prefLabel">antibody technology</a></div><div class="field-item even"><a href="/unews/technology/biomedical-technology" typeof="skos:Concept" property="rdfs:label skos:prefLabel">biomedical technology</a></div></div></div></div><span property="rnews:name schema:name" content="Excelling on the world stage" class="rdf-meta"></span> Tue, 22 Oct 2013 22:03:53 +0000 trevor.kenney 5728 at /unews High school iGEM group /unews/article/high-school-igem-group <div class="field field-name-field-op-author field-type-node-reference field-label-hidden"><div class="field-items"><div class="field-item even" rel="rnews:creator schema:creator"><div class="view view-openpublish-related-content view-id-openpublish_related_content view-display-id-block_1 view-dom-id-a7db58eeed78a4bef9fd4c78345c9976"> <div class="view-content"> <div class="views-row views-row-1 views-row-odd views-row-first views-row-last"> <div class="views-field views-field-title"> <span class="views-label views-label-title">by</span> <span class="field-content"><a href="/unews/profile/trevor-kenney">Trevor Kenney</a></span> </div> <div class="views-field views-field-created"> <span class="field-content">July 11, 2012</span> </div> </div> </div> </div></div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"> <div class="field-items"> <div class="field-item even" property="rnews:articlebody schema:articleBody"> <p>A group of Lethbridge and area high school students who want to take NASA technology and use it to help reduce the affects of Type 1 Diabetes recently came away from an international competition with an award for their research presentation -- and will be further recognized by the Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ of Lethbridge with $36,000 worth of scholarships ($1,000 per student).<br> <br> Six students, members of the Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ of Lethbridge 36-person High School iGEM (International Genetically-engineered Machines) team made their first trip to the Indianapolis, IN contest as the only Canadian contingent, and presented their take on how to use an innovative, implantable capsule (developed by NASA to release medication in space) to manage the release of insulin for people with Type 1 Diabetes.</p><p><div class="image-caption-container" style="width:500px;"><img src="/unews/sites/default/files/main/articles/hs-igem.jpg" alt="High school iGEM" title="The U of L High School iGEM Team. Back row (from L to R) Yoyo Yao, Erin Kwan, Janelle Veenendaal, Chris Isaac, Dax Law, Devan Carrier, Brianna Carrels, Trisha Bouma. Middle Row (from L to R) Orion Sehn, Branden Black, Marissa Guzzi, Cassandra Logue, Shammamah Hossain, Maya Many Grey Horses, Elaine Bird. Front Row (from L to R) Dawson Meyer, Erin Kelly, Brooke Heatherington, Alycia Amatto, Wesley Mosimann, Katelyn Harder. Missing in photo are Natalia Mitura, Iain Sander, Gerardo Karari Balderas Figueroa, Carissa Kirk, Corbin Chenger, Alli Herauf, Riley Martens, Jared Sparkes, Teddi Reynolds and Marie Cooney."><div class="image-caption">The U of L High School iGEM Team. Back row (from L to R) Yoyo Yao, Erin Kwan, Janelle Veenendaal, Chris Isaac, Dax Law, Devan Carrier, Brianna Carrels, Trisha Bouma. Middle Row (from L to R) Orion Sehn, Branden Black, Marissa Guzzi, Cassandra Logue, Shammamah Hossain, Maya Many Grey Horses, Elaine Bird. Front Row (from L to R) Dawson Meyer, Erin Kelly, Brooke Heatherington, Alycia Amatto, Wesley Mosimann, Katelyn Harder. Missing in photo are Natalia Mitura, Iain Sander, Gerardo Karari Balderas Figueroa, Carissa Kirk, Corbin Chenger, Alli Herauf, Riley Martens, Jared Sparkes, Teddi Reynolds and Marie Cooney.</div></div> </p><p>The group plans to engineer a bacteria that will secrete insulin in response to a person's glucose levels, then house it in the NASA biocapsule (so it is contained and not flowing freely in the bloodstream) where it will safely dispense insulin and could reduce the need for the continuous monitoring, injections and other challenges currently experienced by the hundreds of millions of people worldwide with diabetes.<br> <br> Bold? Absolutely. Can it be done? That's what the group intends to find out.<br> <br> That's why the U of L is rewarding them with scholarships – to help them pursue their interest in science and research at the U of L.<br> <br> The $1,000 scholarship credit per student covers the cost of about two courses, and is available upon their successful application and acceptance to the Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬. The students will be presented with their awards at a brief ceremony that takes place Wednesday, July 11 beginning at 4 p.m. in Anderson Hall, room AH100 (Andy's Place).<br> <br> "When the iGEM competition expanded to include high school students, the U of L saw an opportunity to follow suit and this year 36 students participated in the program," says Dr. Andy Hakin, the U of L's provost and vice president (academic). "Not only does this provide valuable hands-on learning opportunities, but it also augments the existing Alberta science curriculum. We are happy to be able to extend this world-class program into local high schools, exposing younger students to the unique opportunities available by pursuing a science education."<br> <br> Team spokesperson Erin Kelly, a recent Catholic Central High School graduate entering fist year at the U of L in the fall, says the group brainstormed ideas with U of L iGEM team members and chemistry and biochemistry researchers that had a combination of what she describes as 'do-ability' and social relevance. They also looked to past iGEM projects for inspiration, since the work created by all iGEM teams worldwide is in the public domain and archived in the interests of conducting innovative research.<br> <br> "A team at Berkeley created bacteria that could produce haemoglobin (a key component of blood) to function as a new type of red blood cell," says Kelly. "We would like to try this with the cells in the pancreas, which were damaged by the onset of Type 1 Diabetes. Another team from Missouri had figured out how to get the cell to detect glucose, which would let the cell know when there is too much sugar. Once glucose is detected, we could work on secreting insulin."<br> <br> Kelly says the NASA capsule is a perfect place to house the bacteria, sustain it, and act as a filter to move the insulin from the capsule to the person.<br> <br> "We would have a lot of work to do before we can get to that stage, because we have to engineer some other steps into the process. We expect that a project like this would be one that could carry through a few years of iGEM teamwork, and could be used by other teams to move their own projects forward."<br> <br> At the U of L, the iGEM team concept has evolved to a point where the university-level group runs its own funded lab, regularly places in the top levels of international competitions, and has provided a significant boost to undergraduate students who wish to pursue further research at a masters level.<br> <br> Their ongoing project involves engineering bacteria to recognize – and consume – harmful materials in oilsands tailings ponds.<br> <br> "We have welcomed high-school researchers to the U of L iGEM group in the past, but to have this large number of interested and engaged students is a really great experience for all of us," says Dr. Hans-Joachim Wieden, a U of L biochemistry researcher and one of the faculty supervisors for both groups. "The additional support the students are receiving from the Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ in the form of scholarships is a great indicator of their achievement, and we look forward to having them join us as students when they begin their university studies. "</p><p><strong>STUDENT NAMES, GRADES AND HIGH SCHOOL AFFILIATION </strong><br> <br> <strong>Lethbridge Collegiate Institute</strong><br> <br> Dax Law 11<br> Erin Kwan 12<br> Cassandra Logue 11<br> Devan Carrier 11<br> Teddi Reynolds 12<br> Gerardo Karari Balderas Figueroa 11<br> <br> <strong>Catholic Central High School</strong><br> <br> Erin Kelly 12<br> Elaine Bird 11<br> Corbin Chenger 12<br> Carissa Kirk 10<br> Brooke Heatherington 11<br> Riley Martens 12<br> Marissa Guzzi 12<br> Branden Black 11<br> Katelyn Harder 11<br> Natalia Mitura 12<br> Iain Sander 11<br> Marie Cooney 11<br> Alycia Amatto 11<br> <br> <strong>Chinook High School</strong><br> <br> Brianna Carrels 10<br> Yoyo Yao 11<br> Chris Isaac 11<br> Jared Sparkes 11<br> Maya Many Grey Horses 11<br> Wesley Mosimann 11<br> Dawson Meyer 11<br> Alli Herauf 10<br> <br> <strong>Winston Churchill High School</strong><br> <br> Shammamah Hossain 11<br> Orion Sehn 10<br> <br> <strong>Immanuel Christian High School</strong><br> <br> Janelle Veenendaal 11<br> Trisha Bouma 11 </p> </div> </div> </div> <div class="field-group-format group_related_topics field-group-div group-related-topics block-title-body speed-fast effect-none"><h2><span>Related Topics</span></h2><div class="field field-name-opencalais-city-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">City:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/city/indianapolis" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Indianapolis</a></div></div></div><div class="field field-name-opencalais-facility-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Facility:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/facility/lethbridge-collegiate-institute" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Lethbridge Collegiate Institute</a></div><div class="field-item odd"><a href="/unews/facility/anderson-hall" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Anderson Hall</a></div><div class="field-item even"><a href="/unews/facility/university-lethbridge" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ of Lethbridge</a></div></div></div><div class="field field-name-opencalais-organization-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Organization:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/organization/lethbridge-collegiate-institute" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Lethbridge Collegiate Institute</a></div><div class="field-item odd"><a href="/unews/organization/national-aeronautics-and-space-administration" typeof="skos:Concept" property="rdfs:label skos:prefLabel">National Aeronautics and Space Administration</a></div><div class="field-item even"><a href="/unews/organization/university-lethbridge" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Ãâ·Ñ¸£Àû×ÊÔ´ÔÚÏß¿´Æ¬ of Lethbridge</a></div><div class="field-item odd"><a href="/unews/organization/catholic-central-high-school" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Catholic Central High School</a></div></div></div><div class="field field-name-opencalais-person-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Person:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/person/maya-many" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Maya Many</a></div><div class="field-item odd"><a href="/unews/person/trisha-bouma" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Trisha Bouma</a></div><div class="field-item even"><a href="/unews/person/marie-cooney" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Marie Cooney</a></div><div class="field-item odd"><a href="/unews/person/carissa-kirk" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Carissa Kirk</a></div><div class="field-item even"><a href="/unews/person/elaine-bird" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Elaine Bird</a></div><div class="field-item odd"><a href="/unews/person/erin-kelly" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Erin Kelly</a></div><div class="field-item even"><a href="/unews/person/erin-kwan" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Erin Kwan</a></div><div class="field-item odd"><a href="/unews/person/hans-joachim-wieden" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Hans-Joachim Wieden</a></div><div class="field-item even"><a href="/unews/person/riley-martens" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Riley Martens</a></div><div class="field-item odd"><a href="/unews/person/gerardo-karari-balderas-figueroa" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Gerardo Karari Balderas Figueroa</a></div><div class="field-item even"><a href="/unews/person/corbin-chenger" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Corbin Chenger</a></div><div class="field-item odd"><a href="/unews/person/katelyn-harder" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Katelyn Harder</a></div><div class="field-item even"><a href="/unews/person/wesley-mosimann" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Wesley Mosimann</a></div><div class="field-item odd"><a href="/unews/person/brooke-heatherington" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Brooke Heatherington</a></div><div class="field-item even"><a href="/unews/person/brianna-carrels" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Brianna Carrels</a></div><div class="field-item odd"><a href="/unews/person/branden-black" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Branden Black</a></div><div class="field-item even"><a href="/unews/person/natalia-mitura" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Natalia Mitura</a></div><div class="field-item odd"><a href="/unews/person/cassandra-logue" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Cassandra Logue</a></div><div class="field-item even"><a href="/unews/person/janelle-veenendaal" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Janelle Veenendaal</a></div><div class="field-item odd"><a href="/unews/person/marissa-guzzi" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Marissa Guzzi</a></div><div class="field-item even"><a href="/unews/person/chris-isaac" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Chris Isaac</a></div><div class="field-item odd"><a href="/unews/person/jared-sparkes" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Jared Sparkes</a></div><div class="field-item even"><a href="/unews/person/andy-hakin" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Andy Hakin</a></div><div class="field-item odd"><a href="/unews/person/alycia-amatto" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Alycia Amatto</a></div><div class="field-item even"><a href="/unews/person/dawson-meyer" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Dawson Meyer</a></div></div></div><div class="field field-name-opencalais-position-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Position:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/position/provost-and-vice-president" typeof="skos:Concept" property="rdfs:label skos:prefLabel">provost and vice president</a></div><div class="field-item odd"><a href="/unews/position/biochemistry-researcher" typeof="skos:Concept" property="rdfs:label skos:prefLabel">biochemistry researcher</a></div><div class="field-item even"><a href="/unews/position/team-spokesperson" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Team spokesperson</a></div></div></div><div class="field field-name-opencalais-product-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Product:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/product/nasa-capsule" typeof="skos:Concept" property="rdfs:label skos:prefLabel">NASA capsule</a></div></div></div><div class="field field-name-opencalais-provinceorstate-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">ProvinceOrState:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/province-or-state/alberta" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Alberta</a></div><div class="field-item odd"><a href="/unews/province-or-state/missouri" typeof="skos:Concept" property="rdfs:label skos:prefLabel">Missouri</a></div></div></div><div class="field field-name-opencalais-technology-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Technology:&nbsp;</div><div class="field-items"><div class="field-item even"><a href="/unews/technology/nasa-technology" typeof="skos:Concept" property="rdfs:label skos:prefLabel">NASA technology</a></div></div></div></div><span property="rnews:name schema:name" content="High school iGEM group" class="rdf-meta"></span> Wed, 11 Jul 2012 21:22:21 +0000 trevor.kenney 3182 at /unews