UNews - Massachusetts

iGEM team celebrates North American Regional victory

trevor.kenney — Mon, 07 Oct 2013 21:10:49 +0000

The ��Ѹ��Դ��߿�Ƭ of Lethbridge has further cemented its reputation as a leader in the teaching and research of synthetic biology by capturing first place at the 2013 North American iGEM Regional Jamboree in Toronto, Ont. this past weekend.

The competition, held at the ��Ѹ��Դ��߿�Ƭ of Toronto, featured teams from across Canada and the United States. The U of L team of Dustin Smith, Graeme Glaister, Jenna Friedt, Suneet Kharey, Harland Brandon and Zak Stinson will now move on to the international competition, which will be held at the Massachusetts Institute of Technology (MIT) in Boston, Mass. Nov. 1-4.

“This certainly shows that bioengineering research and the aggressive approach we’ve taken to study this field is working at the U of L, and that the RNA Institute is playing a key role in both enabling research and training students,” says Dr. H.J. Wieden, director of the Alberta RNA (Ribonucleic acid) Research and Training Institute (ARRTI) at the U of L, the Innovates Centre of Research Excellence (iCORE) Chair of Bioengineering and faculty advisor for the U of L’s iGEM teams. “The ��Ѹ��Դ��߿�Ƭ is poised to continue to be at the forefront of this emerging field.”

The U of L team’s project includes developing a bioengineering part that compresses genetic information – essentially working like a zip drive. Every gene needs DNA, but there is only so much DNA that will fit in a cell. This novel part may allow future bioengineers more flexibility in their work.

Additionally, the U of L team developed software that quickly determines what DNA is compatible to compress together.

“Each year we are also tasked with exploring the social implications of our project. Our team sought to ensure that our part could not be misused to hide dangerous genes,” says team member Harland Brandon (BSc’13), a first-year master’s student and Winston Churchill High School graduate. “We hypothesized that our part could be used to hide dangerous sequences, such as Ricin or Ebola, from gene synthesis companies. We then took it a step further and actually consulted with gene synthesis companies, U of L Risk and Safety Services and even a representative from the Federal Bureau of Investigations (FBI). Not only do we see our project benefitting the field, but we found through our critical analysis that the potential for misuse is not possible.”

In addition to winning the overall Regional Overgrad award, the U of L also claimed the award for best Wiki (website explaining their project).

iGEM is the premier competition for young scientists interested in the emerging field of synthetic biology, which is quickly leading to new discoveries that will diversify key economic sectors such as pharmaceutical, agriculture, medical diagnostics, clean energy and resource extraction. It also facilitates scientific research and education by establishing and operating the Registry of Standard Biological Parts, a community collection of open source biological components.

The organization promotes the advancement of science and education by developing an international open community of students and practitioners in schools, laboratories, research institutes and industry.

Earlier this year, a team of Lethbridge high school students was awarded the coveted Green Brick grand prize at iGEM’s High School Jamboree.

New Biological Information Processing program presents incredible oppportunity

trevor.kenney — Tue, 24 Sep 2013 21:12:09 +0000

A new program in the ��Ѹ��Դ��߿�Ƭ of Lethbridge’s Canadian Centre for Behavioural Neuroscience (CCBN) presents an incredible opportunity for the next generation of scientists.

The Biological Information Processing (BIP): From Genome to Systems Level program (www.uleth.ca/artsci/neuroscience/student-opportunities), funded by the Natural Sciences & Engineering Research Council of Canada (NSERC) through its Collaborative Research and Training Experience (CREATE) program, is currently seeking exceptional graduate students and post-doctoral fellows.

“In this program, students learn from an unparalleled group of mentors who are world leaders in their fields,” says Dr. Robert Sutherland, program director, NSERC CREATE Biological Information Processing, and Chair of the Department of Neuroscience.

Graduate student Rajat Thapa (BSc '12) is working with neuroscience researcher Dr. Aaron Gruber as part of the BIP program.

Citing neuroscience, biology, epigenetics, cancer research and neurotechnology development as fields of supervisor expertise, Sutherland says the unique approach of the BIP program makes it attractive to students who are looking at gaining hands-on experience that is easily translatable to industry.

“The program stands apart from the standard academic track because it provides opportunities for science entrepreneurship, industry contact and the translation of science to industry,” he says. “It also offers a very competitive stipend to qualified applicants.”

Rajat Thapa (BSc ’12) is a graduate student working under the supervision of neuroscientist Dr. Aaron Gruber. His research focus is on decision making and he relishes the opportunity to not only learn alongside some of the world’s leading neuroscientists, but to put those lessons into practice.

“The program allowed me to jump right into research,” says Thapa, originally from Nepal. “The focus is on learning through independently leading a research project. It’s helping me gather tools in terms of methods, data analysis techniques and creative and critical thinking necessary to pursue the questions I hope to answer someday.”

Students who have a background in neuroscience, cell biology, imaging science, physiology, biochemistry and computation are urged to apply for acceptance to the School of Graduate Studies (www.uleth.ca/graduatestudies/apply) at the ��Ѹ��Դ��߿�Ƭ of Lethbridge and simultaneously to the NSERC CREATE Biological Information Processing Program. The application deadline for MA, MSc and PhD candidates for the Spring 2014 cohort is Oct. 1, 2013. Post-doctoral candidates can apply at anytime.

“The world-class expertise that the students have access to will benefit them throughout their subsequent careers,” says Sutherland. “To have this collection of researchers right here in Canada, in southern Alberta, is quite remarkable, and our belief is that we can provide our students with the toolkit necessary to produce the next generation of innovators in neuroscience.”

High school iGEM team best in the world

trevor.kenney — Tue, 02 Jul 2013 20:23:42 +0000

A team of Lethbridge high school students has been awarded the coveted Green Brick grand prize at the iGEM High School Jamboree – an international competition for young synthetic biologists at the Massachusetts Institute of Technology (MIT) in Boston, MA.

The team was judged on its efforts to create a longer lasting form of Oxytocin – a hormone most-commonly known for its use in aiding childbirth. Oxytocin, unfortunately, has a very short half-life meaning the hormone degrades quickly and soon becomes unstable, making it expensive and difficult to store.

The Lethbridge High School team together with their ��Ѹ��Դ��߿�Ƭ of Lethbridge undergraduate student and graduate student advisors and their faculty advisor, Dr. HJ Wieden, successfully developed a genetic circuit (BioBricks) to reprogram a harmless laboratory strain of the common bacterium Escherichia coli to express a stabilized variant of Oxytocin. Details about their project and the team itself can be found on their project website (wiki) http://2013hs.igem.org/Team:Lethbridge_Canada

In addition to being named the top team at the competition, the Lethbridge team also was awarded prizes for the "Best Bio Brick" and "Best Wiki". A total of 30 international teams competed at the event last weekend.

The iGEM Foundation fosters scientific research and education through organizing and operating the iGEM Competition, the premier student synthetic biology competition. It also facilitates scientific research and education by establishing and operating the Registry of Standard Biological Parts, a community collection of open source biological components.

The organization promotes the advancement of science and education by developing an international open community of students and practitioners in schools, laboratories, research institutes and industry.

"One of the real values of the U of L's commitment to the iGEM program is that it is building bridges between high school and university experiences," say Dr. HJ Wieden, a U of L synthetic biology researcher who served as an advisor to the team. "These exceptional students will be the innovators and entrepreneurs who will add tremendous value to Alberta's economy and quality of life in the future."

Students from the Lethbridge team represented various Lethbridge high schools including Chinook High School, Winston Churchill High School, Catholic Central High School and Lethbridge Collegiate Institute. The team has successfully applied for funding from Alberta Innovates Technology Futures (geekStarter) to support their project.

"This result is absolutely exceptional, though I am not surprised. Previous iGEM competitions have placed ��Ѹ��Դ��߿�Ƭ of Lethbridge undergraduate and our Lethbridge high school teams among the best in the world on multiple occasions," says U of L President and Vice-Chancellor Mike Mahon. "The ��Ѹ��Դ��߿�Ƭ of Lethbridge has a strong track record of attracting world-leading faculty like Dr. Wieden and we are committed to partnering with the community through programs like the iGEM High School Jamboree. It also illustrates that our local high schools are producing some incredible young scientists."

The Lethbridge high school team plans on continuing its Oxytocin project next year.

Alumni earn spots in Oh Canada exhibition

trevor.kenney — Mon, 18 Jun 2012 17:35:46 +0000

Oh, Canada is the largest exhibition of contemporary Canadian art to ever take place in the United States. Among the 62 artists included are three graduates of the ��Ѹ��Դ��߿�Ƭ of Lethbridge's Faculty of Fine Arts.

Artists David Hoffos (BFA '94), Mary-Anne McTrowe (BFA '98) and Daniel Wong (BFA '03) travelled to North Adams, Mass. at the end of May for the opening of the exhibition.

The Massachusetts Museum of Contemporary Art (MASS MoCA) is known globally for showing the very best art of our time. Occupying a vast network of 19th century factory buildings, MASS MoCA's galleries boast more than 100,000 square feet of exhibition space. With a strong focus on new art, the museum has become a destination for those seeking unique, fresh and challenging encounters with contemporary art.

David Hoffos will show works from his Scenes from the House Dream at Oh Canada this fall.

"We think it is an honour to be included in this exhibition, considering Denise Markonish (the curator of Oh, Canada) did more than 400 studio visits in determining the lineup," says Wong.

Known together as the 'art-ernative' folk-rock band The Cedar Tavern Singers AKA Les Phonoréalistes, McTrowe and Wong have worked collaboratively since 2006. They are among the artists who created new works specifically for the exhibition. In addition to performing at the opening of Oh, Canada, the duo released a new album of songs relating to the museum.

"The album features four songs about and related to MASS MoCA: 'Oh Canada, Oh Canada' is our interpretation of what a theme song for the Oh, Canada exhibition might be; 'MASS MoCA' is about the history of the site that MASS MoCA inhabits; and 'Gravity is a Force to be Reckoned With' and 'Truisms' are about Iñigo Manglano-Ovalle and Jenny Holzer, respectively – two artists who have had exhibitions at MASS MoCA. The album cover itself is a riff on Bachman-Turner Overdrive," explains McTrowe.

Though it may come as a surprise to some, Lethbridge is a hotbed for contemporary art production in Canada.

"For as long as I've lived here, Lethbridge has had strong contemporary artists – people who contend on the national and international stage, so I'm not surprised Lethbridge artists are included in Oh, Canada. In fact, I'm honoured to have been chosen, especially considering there are so many great artists here," says Hoffos.

Hoffos has received widespread national acclaim for his large-scale, multimedia installations. From 2008 to 2011 his exhibition, Scenes from the House Dream, toured Canada debuting at the Southern Alberta Art Gallery (SAAG) and showing at major institutions across the country, including the National Gallery of Canada. For Oh, Canada, Hoffos presents works from Scenes from the House Dream; a snapshot of his practice representative of his larger body of work.

"Oh, Canada is a celebration for the whole country. It's the first time an exhibition like this has happened south of the border and it's never happened in Canada either, so it's a special moment not just for the artists in the exhibition, but also for contemporary art in Canada," he says. "My hope is that this exhibition demonstrates that cutting-edge contemporary art production can happen anywhere, including Lethbridge."

Oh, Canada opened May 27 at MASS MoCA and is on view until Apr. 1, 2013. For more info: www.massmoca.org

This story first appeared in the June 2012 issue of the Legend. For a look at the entire issue in flipbook format, follow this link.

Taking the Fear out of FOIP

trevor.kenney — Fri, 04 Nov 2011 20:46:09 +0000

You've seen her before… you know you have… but where? Karen Mahar gets that a lot lately.

The long-time Faculty of Fine Arts employee has recently traded in one administrative skill set for another, taking on the role of Privacy Co-ordinator and Policy Analyst. Her primary responsibility is managing the Freedom of Information and Protection of Privacy (FOIP) Act.

Nobody wishes to be a FOIP officer the same way kids pine to be firefighters or doctors, but Mahar says her interest in the position was the appeal to work on research, policies and processes.

"I started 12 years ago at the U of L as a casual employee and ultimately moved into an administrative position in the dean's office in the Faculty of Fine Arts," she says. "During that time, I earned a BA and an MA with designs on a position that gave me the opportunity to brainstorm and connect more with the ��Ѹ��Դ��߿�Ƭ community on a different level."

Karen Mahar is the new Privacy Co-ordinator and Policy Analyst.

Mahar says that when the chance came up to apply for this new role, she jumped in with both feet.

"It involves research, which I love, and it also provides an opportunity to write and to participate in a number of interesting projects."

Mahar began in August and will succeed Rita Law, who, after establishing the office, is retiring in December. As they work through the transition, Mahar says that Law's work to build the foundation of the office and get people on board with FOIP and its processes has been very helpful.

"She is an invaluable resource, and has been an excellent and very patient teacher," she says. "I don't want people to think of FOIP as a four letter word. My goal in the role is to pick up where Rita leaves off, and work on the awareness and the acceptance of the fact that this is a law, it is not optional. We need to work with it, and not fear it or avoid it. I want to bring a level of comfort and understanding to people's awareness about the laws, so that it becomes part of people's regular job processes."

To help take the fear out of FOIP, Mahar is hosting a series of seminars on FOIP and its various applications. Her talks (FOIP for Faculty is Wednesday, Nov. 2 at noon in AH176, followed by a Friday, Nov. 4 FOIP Free-for-All at noon in AH177) target specific groups, including faculty, front-line employees and anyone who wants to learn more about how to apply FOIP regulations to their work.

"I have to be honest, FOIP scared me, as it seems to scare everyone at one point or another," says Mahar. "However, the more I got into it, and the more I've come to understand how the process works, I love it. I see why it makes sense and its practical application in numerous areas on campus. FOIP is very logical and very straightforward."

Mahar wants people to call with questions or comments, and she is willing to conduct specific programming for business units, employee groups or departments on request. Contact her at 403-332-4620 or e-mail karen.mahar@uleth.ca

This story first appeared in the November issue of the Legend. For a look at the Legend in a flipbook format, follow this link.

U of L iGEM team a Regional finalist

trevor.kenney — Thu, 13 Oct 2011 18:19:06 +0000

The ��Ѹ��Դ��߿�Ƭ of Lethbridge's International Genetically Engineered Machine (iGEM) team achieved finalist status at the 2011 Americas Regional Jamboree in Indianapolis, Ind. recently, advancing to the World Championship Jamboree, Nov. 5-7 in Cambridge, Mass.

The U of L iGEM team, led by Dr. HJ Wieden, was one of four schools that achieved finalists status, along with Brown-Stanford, Yale ��Ѹ��Դ��߿�Ƭ and the eventual Regional champion, ��Ѹ��Դ��߿�Ƭ of Washington. Using primarily undergraduate students to compete against a field of mainly masters and doctoral level students, speaks well to the excellence of the U of L team.

Already recognized as one of the top 10 per cent of iGEM teams in the world, the U of L team will now turn its focus to the World Championship Jamboree to be held at the Massachussetts Institute of Technology (MIT) in Cambridge next month.

To check out the U of L's results from Regionals, follow this link.

Mather receives Ingrid Speaker Medal

trevor.kenney — Wed, 18 May 2011 22:00:07 +0000

This year's winner of The Ingrid Speaker Medal is helping science understand the cognition and behaviour of octopuses and other cephalapods.

A world-renowned authority on octopus and squid behaviour, Dr. Jennifer Mather has been profiled in publications like the New York Times and Discover magazine, spoken at the prestigious TED (Technology, Entertainment and Design) conference, and conducted research around the world.

Dr. Jennifer Mather is a world-renowned authority on octopuses.

It's these achievements – and many others – that led to Mather's most recent accolade: The Ingrid Speaker Medal for Distinguished Research, Scholarship or Performance.

For almost three decades, the psychology professor and one-time CAETL Teaching Fellow, has taught thousands of undergraduates at the ��Ѹ��Դ��߿�Ƭ of Lethbridge everything from child development to the psychology of aging, while maintaining a rigorous research program defined by international collaboration and jet-setting to tropical locales. And, at 67, Mather's still as busy as ever.

"I'm probably trying to model what I teach, which is that we have a full lifespan, thank you, and we should use it," she says.

As one of the ��Ѹ��Դ��߿�Ƭ's most accomplished and longest serving faculty members, Mather is an intuitive choice for the prestigious Ingrid Speaker Medal. But the idea of an international expert on squids and octopuses residing at a land-locked university in southern Alberta's dusty prairies is unintuitive, to say the least.

Mather's fascination with cephalopods – a category of boneless marine creatures which includes octupuses, squids and cuttle fish – began long before she set foot in Lethbridge. Growing up in Victoria, B.C., she spent a lot of time at the ocean shore, investigating the critters that dwelled in the water and sand.

As a child, she was certain she'd study marine life in some capacity, but wasn't sure how. Finally, in the last year of an undergraduate biology degree at the ��Ѹ��Դ��߿�Ƭ of British Columbia, Mather took an animal behaviour class that clarified her path.

"Bingo. I said, 'Okay. This is what I want to do.' "

After completing a biology master's degree in octopus behaviour at Florida State ��Ѹ��Դ��߿�Ƭ, she went on to begin a PhD in psychology at Brandeis ��Ѹ��Դ��߿�Ƭ in Massachusetts. Upon completion of post-doctoral research at Brandeis in 1978, Mather and her husband looked to return to Canada with their two children. In 1980 she took up a prestigious ��Ѹ��Դ��߿�Ƭ Research Fellowship at the ��Ѹ��Դ��߿�Ƭ of western Ontario, then spotted a tenure-track position at the U of L five years later and took the leap.

Lethbridge is nowhere near the natural habitats of cephalopods, but it's never been an impediment to Mather. She conducts field work related to squid displays (for instance, how they use their skin colour or tentacle movement to communicate) at the Caribbean island of Bonaire. At the Seattle Aquarium, she collaborates with Roland Anderson to study octopus cognition.

While many of us know octopuses mainly as odd, unique sea creatures, they're a far more intelligent and creative species than given credit. Researchers first realized the octopus's ability to solve problems in the 1960s, but the matter wasn't explored in breadth until the last couple of decades. In the course of her career, Mather has helped prove that octopuses have different personalities, can solve problems (like opening jars to eat food inside) and play.

While Mather is best known for her work on cephalopods, her research is broader: she's also explored how motor control problems can indicate brain dysfunction (like schizophrenia), care issues related to Alzheimer's disease, and successful university teaching. She's also recently co-authored a book about octopuses for the general public, entitled Octopus: The Ocean's Intelligent Invertebrate.

"I have my fingers in a lot of pies," she admits. "I think it came about by accident, but I'm glad it did. I didn't want to be the kind of researcher to sit in a lab and do nothing else. I also think, as a scientist, I have an obligation to help people understand these animals."

This story first appeared in the Legend. For a look at the Legend in a flipbook format, follow this link.

Corkin to give Milner Series address

trevor.kenney — Mon, 09 May 2011 22:28:56 +0000

Dr. Suzanne Corkin, Massachusetts Institute of Technology, appears at the Lethbridge Public Library Monday, May 9, 7 p.m., as the guest speaker for the Brenda Milner Lecture Series.

Corkin, a professor of neuroscience at MIT, is best known for her work with the famous amnesic patient H.M. who suffered from an unusual condition as a result of brain surgery to treat his epilepsy: He was unable to form new long-term memories. Her presentation is titled Aging, Mild Cognitive Impairment and Alzheimer's Disease.

Her research focuses on the multiple memory systems in the brain and involves human patients with neuro-degenerative diseases such as Alzheimer's disease and Parkinson's disease.

In addition to age-related illnesses, Dr. Corkin also studies the processes of healthy aging in relation to the brain.

Vox Musica on stage

trevor.kenney — Tue, 05 Apr 2011 14:50:26 +0000

An unforgettable night of choral music fills Southminster United Church when two great choirs share the stage. Featuring the talents of Vox Musica and the LCI Singers, Joining Forces, epitomizes choral magnificence, Tuesday, Apr. 5 at 8 p.m.

"Karen Hudson, LCI Singers director, proposed the collaboration between our groups for a performance of John Rutter's Mass of the Children," says Glenn Klassen, Vox Musica director. "The piece is so beautiful; it's breathtaking to hear and truly captivates audiences every time. We're thrilled to join the LCI Singers to bring this piece to Lethbridge audiences."

In addition to their collaborative work, each choir performs an eclectic array of pieces to showcase the diversity of their skills.

Tickets are available from the ��Ѹ��Դ��߿�Ƭ Box Office, weekdays from 12:30 to 3:30 p.m. or by calling 403-329-2616. Tickets are also available at the door.

Community teamwork

trevor.kenney — Mon, 21 Mar 2011 18:01:30 +0000

In addition to their collaborative work, each choir performs an eclectic array of pieces to showcase the diversity of their skills.

Tickets are available from the ��Ѹ��Դ��߿�Ƭ Box, weekdays from 12:30 to 3:30 p.m. or by calling 403-329-2616. Tickets are also available at the door.

For a look at the March issue of the Legend in a flipbook format, follow this link.

UNews - Massachusetts

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